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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481511Generated: October 25, 2026

(2S,3S)-3-(5-(1-Cyanocyclopropyl)-2-methoxybenzyl)amino-2-phenylpiperidine dihydrochloride → (2S,3S)-3-(5-(1,1-dicyanoethyl)-2-methoxybenzyl)amino-2-phenylpiperidine Dihydrochloride

https://huagongshe.com/reaction/481511

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,3S)-3-(5-(1-Cyanocyclopropyl)-2-methoxybenzyl)amino-2-phenylpiperidine dihydrochlorideHCID 9954592—
Reactant5-(1,1-Dicyanoethyl)-2-methoxybenzaldehydeHCID 19066494—
Reactant(2S,3S)-2-Phenylpiperidin-3-amine dihydrochlorideHCID 69654807—
Product(2S,3S)-3-(5-(1,1-dicyanoethyl)-2-methoxybenzyl)amino-2-phenylpiperidine DihydrochlorideHCID 86752971—

Reaction Steps

This compound was prepared from Compound 37 and Compound 3 in the same manner of Compound 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789423
Source datasetuspto-grants-1998_08
ORD IDord-484b9066d6e848eaa7bb89daec72436c
Source noteuspto-grants-1998_08