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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481530Generated: October 25, 2026

(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidine → (2S,3S)-1-tert-Butoxycarbonyl-3-[5-(1,1-dimethyl-3-methoxycarbonyl-2-propynyl)-2-methoxybenzyl]amino-2-phenylpiperidine

https://huagongshe.com/reaction/481530

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidineHCID 11311934—
Reactant5-(1,1-Dimethyl-3-methoxycarbonyl-2-propynyl)-2-methoxybenzaldehydeHCID 19066495—
Reactant(2S,3S)-1-tert-Butoxycarbonyl-3-(5-(1-cyanoethyl)-2-methoxybenzyl)amino-2-phenylpiperidineHCID 57028229—
Product(2S,3S)-1-tert-Butoxycarbonyl-3-[5-(1,1-dimethyl-3-methoxycarbonyl-2-propynyl)-2-methoxybenzyl]amino-2-phenylpiperidineHCID 70138749—

Reaction Steps

This compound was prepared from Compound 59 and Compound 17 in the same manner of Compound 18.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789423
Source datasetuspto-grants-1998_08
ORD IDord-7228f35df5f5450390a3563b376b7380
Source noteuspto-grants-1998_08