(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidine → (2S,3S)-1-tert-Butoxycarbonyl-3-[5-(2-propynyl)-2-methoxybenzyl]amino-2-phenylpiperidine

HRID 481542Notes

Reaction equation

[CH2:1]([C:4]1[CH:5]=[CH:6][C:7]([O:12][CH3:13])=[C:8]([CH:11]=1)[CH:9]=O)[C:2]#[CH:3].[NH2:14][C@H:15]1[CH2:20][CH2:19][CH2:18][N:17]([C:21]([O:23][C:24]([CH3:27])([CH3:26])[CH3:25])=[O:22])[C@H:16]1[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1.C(OC(N1CCC[C@H](NCC2C=C(C(C#N)C)C=CC=2OC)[C@@H]1C1C=CC=CC=1)=O)(C)(C)C>>[C:24]([O:23][C:21]([N:17]1[CH2:18][CH2:19][CH2:20][C@H:15]([NH:14][CH2:9][C:8]2[CH:11]=[C:4]([CH2:1][C:2]#[CH:3])[CH:5]=[CH:6][C:7]=2[O:12][CH3:13])[C@@H:16]1[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)=[O:22])([CH3:27])([CH3:25])[CH3:26]