(2S,3S)-3-Amino-1-tert-butoxycarbonyl-2-phenylpiperidine → (2S,3S)-1-tert-Butoxycarbonyl-3-(5-(1-cyano-4-oxa-cyclohexyl)-2-methoxybenzyl)amino-2-phenylpiperidine

HRID 481549Notes

Reaction equation

[C:1]([C:3]1([C:9]2[CH:10]=[CH:11][C:12]([O:17][CH3:18])=[C:13]([CH:16]=2)[CH:14]=O)[CH2:8][CH2:7][O:6][CH2:5][CH2:4]1)#[N:2].[NH2:19][C@H:20]1[CH2:25][CH2:24][CH2:23][N:22]([C:26]([O:28][C:29]([CH3:32])([CH3:31])[CH3:30])=[O:27])[C@H:21]1[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1.C(OC(N1CCC[C@H](NCC2C=C(C(C#N)C)C=CC=2OC)[C@@H]1C1C=CC=CC=1)=O)(C)(C)C>>[C:29]([O:28][C:26]([N:22]1[CH2:23][CH2:24][CH2:25][C@H:20]([NH:19][CH2:14][C:13]2[CH:16]=[C:9]([C:3]3([C:1]#[N:2])[CH2:8][CH2:7][O:6][CH2:5][CH2:4]3)[CH:10]=[CH:11][C:12]=2[O:17][CH3:18])[C@@H:21]1[C:33]1[CH:38]=[CH:37][CH:36]=[CH:35][CH:34]=1)=[O:27])([CH3:32])([CH3:30])[CH3:31]