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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481644Generated: October 27, 2026

Potassium Carbonate → HCID 21268315, compound

https://huagongshe.com/reaction/481644

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
Reactant6-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoleHCID 10059854—
ReactantHCID 11572111HCID 11572111—
SolventDimethylformamideHCID 6228—
ProductHCID 21268315HCID 21268315—

Reaction Steps

The title compound was prepared in a fashion similar to that described in Example 99 using 1-chloro-4-(1H-indole-4-oxy)butane (0.479 g, 2.15 mmol) and 6-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (0.500 g, 2.13 mmol) in the presence of 2.5 equivalents of potassium carbonate (0.742 g, 5.38 mmol) in dimethylformamide at 90° C. Yield 0.220 g (24%) of a tan foam. FDMS m/e=420 (M+ of free base).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789402
Source datasetuspto-grants-1998_08
ORD IDord-d36196f6c88f4dffa5ea97666196e63c
Source noteuspto-grants-1998_08