Potassium Carbonate → HCID 70217236, compound

Participants

Reaction Steps

The title compound was prepared in a fashion similar to that described in Example 1 using (S)-(+)-4-(oxiranylmethoxy)-1H-indole (0.053 g, 0.028 mmol) and the hydrochloride salt of 5-chloro-3-(1,2,3,6-tetrahydropyridin-4-yl)benzo[b]thiophene (0.081 g, 0.028 mmol) using ethanol as reaction solvent and 1.1 equivalents of potassium carbonate (0.043 g, 0.031 mmol). Yield 0.103 g (83%) of a tan foam. mp 93°-97° C. FDMS m/e=438 (M+ of free base). α[D]589 =+7.5 (c=1.06, dimethylsufoxide)

Provenance & Evidence