HRID481661

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13872

5-Methoxyindole

C9H9NO

HCID2723901

Piperidin-4-one--hydrogen chloride--water (1/1/1)

C5H12ClNO2

PRODUCTS

生成物

HCID108029

5-Methoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole

C14H16N2O

PROCEDURE

实验过程

The title compound was prepared in a fashion similar to that described in Preparation 30 from 5-methoxyindole (5.0 g, 34 mmol) and 4-piperidone hydrochloride hydrate (10.0 g, 65 mmol). The product was isolated as a yellow solid. Yield 6.1 g (79%). mp 191°-195° C. FDMS m/e=228 (M+ of free base).

WORKUP

后处理

customThe product was isolated as a yellow solid