Potassium Carbonate → 3-[4-(7-Chloro-3-indolyl)piperidin-1-yl]-1-(4-indolyloxy)propane

Participants

Reaction Steps

The title compound was prepared in a fashion similar to that described in Example 192 from 7-chloro-3-(piperidin-4-yl)-1H-indole (0.34 g, 1.25 mmol), 1-chloro-3-(1H-indole-4-oxy)propane (0.275 g, 1.32 mmol) and potassium carbonate (0.41 g, 3.0 mmol). The product was isolated as a white foam. Yield 240 mg (47%). mp 178°-182° C. FDMS m/e=407 (M+ of free base). HRMS: calc., 408.184265; found, 408.184300

Provenance & Evidence