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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 481695Generated: October 30, 2026

Potassium Carbonate → HCID 21268255, compound

https://huagongshe.com/reaction/481695

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium CarbonateHCID 11430—
ReactantHCID 11310393HCID 11310393—
Reactant4-(3-chloropropoxy)-1H-indoleHCID 11694169—
SolventDimethylformamideHCID 6228—
ProductHCID 21268255HCID 21268255—

Reaction Steps

The title compound was prepared in a fashion similar to that described in Example 99 using 1-chloro-3-(1H-indole-4-oxy)propane (0.499 g, 2.4 mmol) and 7-methyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole (0.509 g, 2.4 mmol) in the presence of 2.0 equivalents of K2CO3 (0.593, 4.3 mmol) in dimethylformamide at 90° C. Yield 0.383 g (41%) of a tan powder. mp 166°-169° C. FDMS m/e=405 (M+ of free base).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05789402
Source datasetuspto-grants-1998_08
ORD IDord-7f65e84ea3614446a27371eb171fd464
Source noteuspto-grants-1998_08