2-Deoxyribose, D- → 2-Deoxy-D-ribitol

Temperature

70 °C

A 100 g (0.75 mole) portion of 2-deoxy-D-ribose was dissolved in 200 ml of water to form an aqueous solution into which 20 g of Raney nickel were added. The thus prepared reaction mixture in an autoclave was heated under a hydrogen pressure of 40 kg/cm2G up to a temperature of 70° C. taking 30 minutes and kept for additional 1 hour at the same temperature and under the same hydrogen pressure. After cooling, the reaction mixture taken out of the autoclave was filtered to remove the solid catalyst and the filtrate, as combined with the washings of the solid catalyst with water, was subjected to removal of the water to give about 100 g of 2-deoxy-D-erythropentitol. The yield of the product was almost quantitative.

1. additionwere added
2. customThe thus prepared reaction mixture in an autoclave
3. temperatureAfter cooling
4. filtrationwas filtered
5. customto remove the solid catalyst
6. customwas subjected to removal of the water

ORD record

ord-33edfa3122164f2da7efb1f91573eba8

Source dataset

uspto-grants-1998_08

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US05789572