HuagongsheHuagongshe Chemistry Print Report · For research reference only
4'-Hydroxyacetophenone → Ethyl 3-(4-hydroxyphenyl)-3-oxopropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4'-Hydroxyacetophenone | HCID 7469 | — |
| Reactant | Diethyl Carbonate | HCID 7766 | — |
| Product | Ethyl 3-(4-hydroxyphenyl)-3-oxopropanoate | HCID 13136494 | — |
Reaction Steps
This novel compound was synthesized by the acylation of 4-hydroxyacetophenone with diethylcarbonate to yield ethyl 4-hydroxybenzoylacetate. Treatment with acetic anhydride and subsequent catalytic hydrogenation yielded the desired product. The experimental details are given below:
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05789608 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-59e5ff46eda542bdad2bbf9f59050de8 |
| Source note | uspto-grants-1998_08 |