HCID 19064359, compound → HCID 18664413, compound

HRID 481939Notes

Reaction equation

HRID 481939 reaction equation
[OH:1][C@H:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C:4](=[CH:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][CH2:10][C@@H:11]2[CH2:21][CH2:22][CH:23]=O)[CH2:3]1.Cl.Cl.[CH3:27][N:28]([CH3:34])[CH:29](C)[CH2:30][O:31][NH2:32]>>[CH3:27][N:28]([CH3:34])[CH2:29][CH2:30][O:31]/[N:32]=[CH:23]/[CH2:22][CH2:21][C@H:11]1[CH2:10][CH2:9][C@H:8]2[C@H:7]3[C@H:16]([CH2:15][CH2:14][C@:12]12[CH3:13])[C@:17]1([CH3:20])[C:4]([CH2:3][C@@H:2]([OH:1])[CH2:19][CH2:18]1)=[CH:5][CH2:6]3

Participants

3

Reactant 2

HCID 19064359HCID 19064359, compoundHCID 88295267HCID 88295267, compound

Product 1

HCID 18664413HCID 18664413, compound

Procedure

The compound (I-k) (0.22 g) was obtained as a white solid, containing 10% of Z isomer from 0.30 g of 3-(3β-hydroxyandrost-5-en-17β-yl)propionaldehyde (prep. 4) and 2-dimethylaminopropoxyamine dihydrochloride using the same method as that described in Ex. 1.

Workup

  1. customThe compound (I-k) (0.22 g) was obtained as a white solid

Sources & evidence

ORD record
ord-3cfd3a8a549a4f60a238dcb1ba5197bd
Source dataset
uspto-grants-1998_08
Patent number
US05792759

Reaction notes

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