HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Methoxyphenyl)-4-(2-nitrophenyl)imidazole → HCID 178488922, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Methoxyphenyl)-4-(2-nitrophenyl)imidazole | HCID 178488923 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178488922 | HCID 178488922 | 102.4% |
Reaction Steps
2-(4-Methoxyphenyl)-4-(2-nitrophenyl)imidazole (10 g) is mixed with EtOH (80 ml) and 5% Pd-C (wet, 2 g). The mixture is shaken under hydrogen at 50 psi for 45 min. then filtered through Celite. The filtrate is evaporated under reduced pressure to yield 2-(4-methoxyphenyl)-4-(2-aminophenyl)imidazole (9.2 g) as a brown solid which is used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05792766 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-98cf92f716584d32a3b44bbdbb725d0f |
| Source note | uspto-grants-1998_08 |