反应详情

To a solution of 2-mercaptobenzothiophene (1.8 g, 10.8 mmol) in toluene under nitrogen was added N-benzylpiperazine (1.88 ml, 10.8 mmol) and the mixture heated at reflux for 1.5 h. Left to cool, concentrated in vacuo and product recrystallised from diethyl ether-hexane to yield the title compound (1.55 g), m.p. 160°-161° C.

1. temperaturethe mixture heated
2. temperatureat reflux for 1.5 h
3. waitLeft
4. temperatureto cool
5. concentrationconcentrated in vacuo and product
6. customrecrystallised from diethyl ether-hexane