Acetyl chloride → HCID 19064512, compound

HRID 481983Notes

Reaction equation

HRID 481983 reaction equation
[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][CH:8]=[C:7]([CH:10]3[CH2:15][CH2:14][N:13]([CH3:16])[CH2:12][CH2:11]3)[C:6]=2[CH:17]=1.[C:18]([Cl:21])(=[O:20])[CH3:19]>>[ClH:21].[CH3:16][N:13]1[CH2:12][CH2:11][CH:10]([C:7]2[C:6]3[CH:17]=[C:2]([NH:1][C:18](=[O:20])[CH3:19])[CH:3]=[CH:4][C:5]=3[O:9][CH:8]=2)[CH2:15][CH2:14]1

Participants

3

Reactant 2

HCID 6367Acetyl chlorideHCID 19064653HCID 19064653, compound

Product 1

HCID 19064512HCID 19064512, compoundYield 68%

Procedure

Beginning with a mixture of 0.018 gm (0.07 mMol) 5-amino-3-(l-methylpiperidin-4-yl)benzofuran and 15 μL (0.21 mMol) acetyl chloride, 0.0147 gm of the title compound were prepared by the procedure of EXAMPLE 18.

Sources & evidence

ORD record
ord-a805dceb556547f18026c29e0a87703c
Source dataset
uspto-grants-1998_08
Patent number
US05792763

Reaction notes

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