Benzenesulfonyl chloride → HCID 19064581, compound

HRID 481984Notes

Reaction equation

[NH2:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][CH:8]=[C:7]([CH:10]3[CH2:15][CH2:14][N:13]([CH3:16])[CH2:12][CH2:11]3)[C:6]=2[CH:17]=1.[C:18]1([S:24]([Cl:27])(=[O:26])=[O:25])[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1>>[ClH:27].[CH3:16][N:13]1[CH2:12][CH2:11][CH:10]([C:7]2[C:6]3[CH:17]=[C:2]([NH:1][S:24]([C:18]4[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=4)(=[O:26])=[O:25])[CH:3]=[CH:4][C:5]=3[O:9][CH:8]=2)[CH2:15][CH2:14]1

Participants

Reactant 2

HCID 7369Benzenesulfonyl chloride

HCID 19064653HCID 19064653, compound

Product 1

HCID 19064581HCID 19064581, compound

Procedure

Beginning with a mixture of 0.018 gm (0.07 mMol) 5-amino-3-(l-methylpiperidin-4-yl)benzofuran and 27 μL (0.21 inMol) phenylsulfonyl chloride, 0.0056 gm of the title compound were prepared by the procedure of EXAMPLE 18.

Sources & evidence

ORD record: ord-2f97f34c971e4032b738c96b4804493a
Source dataset: uspto-grants-1998_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05792763

Reaction notes

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