HCID 19065226, compound → HCID 54570244, compound

Participants

Reaction Steps

21.3 g of 7-ethoxycarbonylmethoxy-5-hydroxy-2-(2-allyl-3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one are dissolved in 300 ml of dimethylformamide. The solution is poured into 2 g of 10% palladium on carbon. The whole is hydrogenated at 50° C. under a pressure of 63×104Pa until the theoretical amount of hydrogen has been absorbed. The mixture is then filtered over Millipore and the solvent is removed by distillation under reduced pressure. The crude residue (21 g) may be used as it is. An analytical sample, obtained by recrystallisation from isopropanol, melts at 138° C.

Provenance & Evidence