HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 22466780, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | 4-[2-(4-Fluorophenyl)-5-(4-piperidinyl)-1H-pyrrol-3-yl]pyridine | HCID 15923094 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 22466780 | HCID 22466780 | — |
Reaction Steps
A solution of 10.0 mg of the product of Example 4 was dissolved in 0.5 ml of pyridine and treated with 2.6 μL of acetic anhydride. The solution was stirred overnight and diluted with 5 ml water and was extracted with ethyl acetate (2×5 ml). The combined organic phase was dried over MgSO4, filtered and concentrated in vacuo to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05792778 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-57ac7c0752af403482d259da23206f15 |
| Source note | uspto-grants-1998_08 |