8-Bromo-1,2,3,4-tetrahydro-6-nitro-2-propyl-5-isoquinolinamine → HCID 10058790, compound

Participants

Reaction Steps

A solution of the product from Example 12 (1.50 g, 4.77 mmol) and 20% Pd on carbon (0.30 g) in 75 mL of MeOH was hydrogenated at room temperature and pressure for 24 hours. The reaction mixture was concentrated and the residue was suspended in iPr2O and collected by filtration to give the title compound as a yellow solid (1.27 g, 93%).

Provenance & Evidence