HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-1-(2,4-difluorophenyl)ethanone → 1-(2,4-Difluorophenyl)-1-(6-cyanobenzothiazol-2-YL)-2-chloroethanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-1-(2,4-difluorophenyl)ethanone | HCID 588083 | — |
| Reactant | Benzothiazole-6-carbonitrile | HCID 10607144 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 1-(2,4-Difluorophenyl)-1-(6-cyanobenzothiazol-2-YL)-2-chloroethanol | HCID 10594049 | — |
Reaction Steps
2-Chloro-2',4'-difluoroacetophenone is added to 6-cyanobenzothiazole in the presence of n-butyllithium to form 1-(2,4-difluorophenyl)-1-(6-cyanobenzothiazol-2-yl)-2-chloroethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05792781 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-b95335b434b1461e932aa4cb92b93d54 |
| Source note | uspto-grants-1998_08 |