HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 1,2,3,4-Tetrahydroquinoline-5,6-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | Quinoline-5,6-diamine | HCID 426874 | — |
| Catalyst | Platinum oxide (PtO) | HCID 82844 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1,2,3,4-Tetrahydroquinoline-5,6-diamine | HCID 22742466 | — |
Reaction Steps
A solution of 5,6-quinolinediamine (12.5 g, 0.065 mol) and sulfuric acid (8 mL) in methanol (250 mL) was treated with platinum oxide (1 g) in a Parr apparatus under hydrogen for 16 hours. An additional 1 g portion of platinum oxide was added and hydrogenation continued for 44 hours additional. Standard work-up gave the 5,6-diaminotetrahydroquinoline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703391B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-71bc07ae0cd34c7fa0e0d08e19635dce |
| Source note | uspto-grants-2004_03 |