Potassium Formate → HCID 69703307, compound

Participants

Reaction Steps

To a solution of the product of Example 24 (794 mg, 1.71 mmol) in 16 mL of absolute ethanol and 3 mL of acetone under N2 was added 10% Pd/C (400 mg) followed by a solution of potassium formate (513 mg, 6.10 mmol) in 1 mL of H2O. After 50 min, the mixture was filtered through a pad of celite and concentrated by rotary evaporation. The residue was partitioned between ethyl acetate and water and the organic layer was washed with brine and dried over Na2SO4. The solvent was removed by rotary evaporation and the residue was purified by silica gel chromatography (1:1 ethyl acetate hexanes) to afford 682 mg of the desired final product.

Provenance & Evidence