化工社化工社 化学情報印刷レポート · 研究参考用
Water → 2-(3-Hydroxy-5-methyl-phenyl)-isoindole-1,3-dione
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Water | HCID 962 | — |
| 反応物 | Phthalic Anhydride | HCID 6811 | — |
| 反応物 | 3-Amino-5-methylphenol | HCID 3018667 | — |
| 溶媒 | Acetic Acid | HCID 176 | — |
| 生成物 | 2-(3-Hydroxy-5-methyl-phenyl)-isoindole-1,3-dione | HCID 18945000 | 80.6% |
反応手順
36.0 g (292 mmol) 3-amino-5-methylphenol and 73.5 g (496 mmol) phthalic acid anhydride were heated for 2 h to boiling under reflux in 280 ml glacial acetic acid. Water was added, it was heated for a short time, allowed to cool and filtered. 59.6 g (80%) 2-(3-hydroxy-5-methyl-phenyl)-isoindole-1,3-dione of Fp 174°-175° C. was obtained.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US05795892 |
| 出典データセット | uspto-grants-1998_08 |
| ORD ID | ord-8a1b06fd11ca42558641f7b5f6be1dc6 |
| 出典メモ | uspto-grants-1998_08 |