HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 10266265, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Sodium cyanoborohydride | HCID 5003444 | — |
| Reactant | [(6-Nitro-5-quinolinyl)amino]oxo-acetic acid ethyl ester | HCID 10085554 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 10266265 | HCID 10266265 | 78% |
Reaction Steps
A solution of the product from Example 85 (5 g, 17.5 mmol) in 80 mL acetic acid was treated with sodium cyanoborohydride (2.2 g, 35 mmol) portionwise under an argon atmosphere and stirred for 4 hours. Water (100 mL) was added to the reaction mixture, and the resulting solid was collected by filtration and dried (3.9 g, 78% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703391B2 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-71a28719b79346798bf640136e8a9bc8 |
| Source note | uspto-grants-2004_03 |