Ammonia → HCID 10674507, compound

Participants

Reaction Steps

The desired compound was prepared according to the method of Example 1, step 3, except substituting 4,4-bis(2-quinolylmethoxy)phenyl)-4-hydroxy-2-butynoic acid methyl ester, prepared as in step 1, for 4,4-bis(4-(2-quinolylmethoxy)phenyl)-pentanoic acid: mp 169°-172° C.; 1H NMR (300 MHz, DMSO--d6) d 5.35 (s, 4H), 7.04 (d, 4H, J=9 Hz), 7.37 (d, 4H, J=9 Hz), 7.63 (m, 4H), 7.78 (m, 2H), 8.00 (m, 4H), 8.40 (d, 2H, J=8 Hz), 13.75 (bs, 1H); MS (DCI--NH3) m/e: 567 (M+H)+. Anal. Calc'd. for C36H26 N2O4. 0.5 H2O: C, 75.12; H, 4.73;N, 4.89. Found: 75.19; H, 4.80; N, 4.60.

Provenance & Evidence