反应详情

A mixture of the product from Example 87 (0.87 g, 3 mmol), methyl iodide (0.51 g, 3.6 mmol) and cesium carbonate (1.17 g, 3.6 mmol) in 15 mL of acetonitrile was stirred at room temperature for 2 hours. The inorganic salts were removed by filtration and the filtrate evaporated. The residue was dissolved in methylene chloride, filtered and evaporated. The product was then used without further purification (0.86 g, 93% yield).

1. customThe inorganic salts were removed by filtration
2. customthe filtrate evaporated
3. dissolutionThe residue was dissolved in methylene chloride
4. filtrationfiltered
5. customevaporated
6. customThe product was then used without further purification (0.86 g, 93% yield)