反应详情

A solution of the product from Example 94 (1.1 g) in 100 mL of acetic acid was treated with 20% Pd/C (0.3 g) and shaken on a Parr apparatus under a hydrogen atmosphere (50 psi) for 15.5 hours. After removing the catalyst by filtration through a celite pad, the filtrate was evaporated and the yellow solide was washed with diethyl ether and dried to give the title compound (0.55 g, 69% yield) mp>285° C.

1. customAfter removing the catalyst
2. filtrationby filtration through a celite pad
3. customthe filtrate was evaporated
4. washthe yellow solide was washed with diethyl ether
5. customdried