HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → Methyl 2-(3-hydroxymethylphenoxy)propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Methyl 2-(3-formylphenoxy)propanoate | HCID 18759681 | — |
| Catalyst | Sodium Methoxide | HCID 10942334 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2-(3-hydroxymethylphenoxy)propionate | HCID 18759680 | 97.5% |
Reaction Steps
By the method of Example 1, Step G, 15.7 g (0.0761 mole) of methyl 2-(3-formylphenoxy)propionate, 0.76 g (0.020 mole) of sodium borohydride, and 0.10 g (0.0018 mole) of sodium methoxide were reacted in 40 mL of methanol, yielding 15.6 g of methyl 2-(3-hydroxymethylphenoxy)propionate as a yellow liquid. The NMR and IR spectra were consistent with the proposed structure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05798316 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-499a31936b394589abd93b0cda809158 |
| Source note | uspto-grants-1998_08 |