HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium borohydride → Methyl 2-(2-hydroxymethyl-4-ethylphenoxy)propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium borohydride | HCID 4311764 | — |
| Reactant | Sodium Methoxide | HCID 10942334 | — |
| Reactant | Methyl 2-(2-formyl-4-ethylphenoxy)propionate | HCID 18981013 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Methyl 2-(2-hydroxymethyl-4-ethylphenoxy)propionate | HCID 18981032 | 52.1% |
Reaction Steps
By the method of Example 1, Step G, 49.16 grams (0.21 mole) of methyl 2-(2-formyl-4-ethylphenoxy)propionate, 2.04 grams (0.054 mole) of sodium borohydride, and 0.79 gram (0.0147 mole) of sodium methoxide were reacted in 100 mL of methanol, yielding 26.06 grams of methyl 2-(2-hydroxymethyl-4-ethylphenoxy)propionate. The NMR spectrum was consistent with the proposed spectrum.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05798316 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-7c113bf556634fd28bafde97c6b31804 |
| Source note | uspto-grants-1998_08 |