HuagongsheHuagongshe Chemistry Print Report · For research reference only
[2-(4-Hydroxyphenyl)-benzofuran-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl] methanone hydrochloride → [2-(4-Hydroxyphenyl)-benzofuran-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [2-(4-Hydroxyphenyl)-benzofuran-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl] methanone hydrochloride | HCID 22743067 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | [2-(4-Hydroxyphenyl)-benzofuran-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]methanol | HCID 12968238 | 84.7% |
Reaction Steps
2.0 g (4.23 mmol) of [2-(4-hydroxyphenyl)-benzofuran-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl] methanone hydrochloride was reduced to the carbinol using the method described in Example 1. This yielded 1.59 g of the title compound as an amorphous powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06703407B1 |
| Source dataset | uspto-grants-2004_03 |
| ORD ID | ord-10db497d9c4d4199971f534be00ffd9a |
| Source note | uspto-grants-2004_03 |