HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl chloroformate → HCID 18981005, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl chloroformate | HCID 6586 | — |
| Reactant | p-Chlorophenacyl bromide | HCID 68303 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | Glycine methyl ester hydrochloride | HCID 122755 | — |
| Product | HCID 18981005 | HCID 18981005 | 27.8% |
Reaction Steps
By substantially following the procedure given in Example 585c using 35 g (150 mmole) of 2-bromo-4'-chloroacetophenone, 20.7 g (160 mmole) of glycine methyl ester hydrochloride, 40.6 g (310 mmole) of diisopropylethyl amine, and 14.2 g (150 mmole) of methyl chloroformate, 12.5 g of the desired compound, an oil, was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05798311 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-beef22803f56414fb7e960a7bbd36c03 |
| Source note | uspto-grants-1998_08 |