HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyethylamine → 2-(N-formyl-N-(2-methoxyethyl)amino)-4'-propoxyacetophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyethylamine | HCID 8018 | — |
| Reactant | Acetic-formic anhydride | HCID 75269 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 2-Bromo-1-(4-propoxyphenyl)ethan-1-one | HCID 14617326 | — |
| Product | 2-(N-formyl-N-(2-methoxyethyl)amino)-4'-propoxyacetophenone | HCID 18980987 | — |
Reaction Steps
By substantially following the procedure of Example 585c using 37 g (≤140 mmole) of 2-bromo-4'-propoxyacetophenone (Example 585b), 16 g (210 mmole) of 2-methoxyethylamine, 22 g (170 mmole) of diisopropylethylamine, and 50 g of formic acetic anhydride mixture (≤350 mmole) 18.5 g of the desired compound, an oil, was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05798311 |
| Source dataset | uspto-grants-1998_08 |
| ORD ID | ord-69d1a7848c5247aea76f0eff1914e3e1 |
| Source note | uspto-grants-1998_08 |