1-Hexanamine, hydrochloride → HCID 178444829, compound

HRID 482645Notes

Reaction equation

HRID 482645 reaction equation
Cl.[CH2:2]([NH2:8])[CH2:3][CH2:4][CH2:5][CH2:6][CH3:7].[N-:9]([C:12]#[N:13])[C:10]#[N:11].[Na+]>C(O)CCC>[C:10]([NH:9][C:12](=[NH:13])[NH:8][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH3:7])#[N:11]

Participants

4

Reactant 2

HCID 673421-Hexanamine, hydrochlorideHCID 4350929Sodium dicyanamide

Product 1

HCID 178444829HCID 178444829, compound

Reagents, catalysts & solvents 1

HCID 2631-ButanolSolvent

Procedure

A mixture of hexylamine hydrochloride (63.5 g.), sodium dicyanamide (44.5 g.) and butanol (200 ml.) was heated at reflux for 18 hours and then cooled. The mixture was filtered and the filtrate was evaporated to dryness. The residue was stirred with water and the isoluble solid was collected and crystallised from aqueous ethanol, to give 3-cyano-1-hexylguanidine, m.p. 103°-105°.

Workup

  1. temperaturewas heated
  2. temperatureat reflux for 18 hours
  3. temperaturecooled
  4. filtrationThe mixture was filtered
  5. customthe filtrate was evaporated to dryness
  6. customthe isoluble solid was collected
  7. customcrystallised from aqueous ethanol

Sources & evidence

ORD record
ord-c9a256cf7c87403c8326f0eba79ae3ee
Source dataset
uspto-grants-1986_03
Patent number
US04574123

Reaction notes

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