Hydrochloric Acid → 2-Chloro-5-[2,3-dichloro-4-(2-propen-1-yloxy)benzoyl]-N-[(dimethylamino)methylene]benzenesulfonamide

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Reaction Steps

5.6 g (40 mmol) of allyl bromide are added dropwise, with magnetic stirring, to a mixture of 13.1 g (30 mmol) of 4-hydroxy-3'-dimethylaminomethyleneaminosulfonyl-2,3,4'-trichlorobenzophenone, 5.0 g (36 mmol) of ground potassium carbonate and 50 ml of dry dimethylformamide at room temperature, and the mixture is stirred for about 8 hours. The pale yellow suspension is then stirred in portions into a mixture of 400 ml of ice-water and 100 ml of 2N hydrochloric acid, and the precipitate is filtered off. Colorless crystals, melting point 141°-142° C. (from acetone/ethanol).

Provenance & Evidence