Thiourea → HCID 178483278, compound

HRID 482657Notes

Reaction equation

HRID 482657 reaction equation
[ClH:1].Cl.[CH3:3][N:4]([CH2:6][C:7]1[CH:12]=[CH:11][N:10]=[C:9]([CH2:13][Cl:14])[CH:8]=1)[CH3:5].[NH2:15][C:16]([NH2:18])=[S:17]>C(O)C>[ClH:14].[ClH:1].[ClH:14].[CH3:3][N:4]([CH2:6][C:7]1[CH:12]=[CH:11][N:10]=[C:9]([CH2:13][NH:18][C:16](=[NH:15])[SH:17])[CH:8]=1)[CH3:5]

Participants

4

Reactant 2

HCID 2723790ThioureaHCID 132926032-Chloromethyl-4-dimethylaminomethylpyridine dihydrochloride

Product 1

HCID 178483278HCID 178483278, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

4-Dimethylaminomethyl-2-chloromethylpyridine dihydrochloride is reacted with thiourea in ethanol under reflux. Removal of the ethanol yields 4-dimethylaminomethyl-2-pyridylmethyl isothiourea trihydrochloride.

Workup

  1. temperatureunder reflux
  2. customRemoval of the ethanol

Sources & evidence

ORD record
ord-36c97227927945d1b43d9225bc75e9cc
Source dataset
uspto-grants-1986_03
Patent number
US04574126

Reaction notes

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