Calcium Carbonate → HCID 20244615, compound

HRID 482676Notes

Reaction equation

HRID 482676 reaction equation
Cl[C:2]([O:4][CH:5](C)[CH2:6][Cl:7])=[O:3].[NH2:9][C:10]1[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][C:11]=1[N+:17]([O-:19])=[O:18].[C:20](=O)([O-])[O-].[Ca+2]>O1CCOCC1>[N+:17]([C:11]1[CH:12]=[C:13]([OH:16])[CH:14]=[CH:15][C:10]=1[NH:9][C:2](=[O:3])[O:4][CH2:5][CH:6]([Cl:7])[CH3:20])([O-:19])=[O:18]

Participants

5

Reactant 3

HCID 10112Calcium CarbonateHCID 571995Formic acid, chloro-, 2-chloro-1-methylethyl esterHCID 37588824-Amino-3-Nitrophenol

Product 1

HCID 20244615HCID 20244615, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

85 g (0.54 mole) of α-methyl-β-chloroethyl chloroformate are added dropwise to 77 g (0.5 mole) of 4-amino-3-nitrophenol and 27 g of calcium carbonate in 250 ml of dioxane at 70° C. After 2 hours at 90° C., the inorganic salts are filtered off hot and the filtrate is concentrated completely. The desired intermediate product is thereby obtained in the form of a reddish oil and is used as such in the following stage.

Workup

  1. filtrationthe inorganic salts are filtered off hot
  2. concentrationthe filtrate is concentrated completely

Sources & evidence

ORD record
ord-6d81fe52fb7c4153bf1c8202ffe6abaf
Source dataset
uspto-grants-1986_03
Patent number
US04575378

Reaction notes

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