HuagongsheHuagongshe Chemistry Print Report · For research reference only
Calcium Carbonate → gamma-chloropropyl N-(5-chloro-4-hydroxy-2-nitrophenyl)-carbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Calcium Carbonate | HCID 10112 | — |
| Reactant | Carbonochloridic acid, 3-chloropropyl ester | HCID 69399 | — |
| Reactant | 4-Amino-2-chloro-5-nitrophenol | HCID 18950617 | — |
| Solvent | 1,2-Dimethoxyethane | HCID 8071 | — |
| Product | gamma-chloropropyl N-(5-chloro-4-hydroxy-2-nitrophenyl)-carbamate | HCID 20244610 | — |
Reaction Steps
37.7 g (0.2 mole) of 6-chloro-3-nitro-4-aminophenol are dissolved in 120 ml of dimethoxyethane, 11 g of calcium carbonate are added and 32 g of γ-chloropropyl chloroformate are added dropwise at 70° C. After 1 hour at 90° C., the mixture is filtered hot and the filtrate is stirred into 300 ml of ice-water. The initially oily product crystallises after a short time.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04575378 |
| Source dataset | uspto-grants-1986_03 |
| ORD ID | ord-d7662345536f47cfb421a57164b00f62 |
| Source note | uspto-grants-1986_03 |