反应详情

3',4',-Dihydro-4'-hydroxy-7'-fluorospiro[imidazolidine-4,1'(2'H)-naphthalene]2,5-dione (3.2 g., 0.013 mole) was added to 75 ml. of toluene containing a trace of -toluenesulfonic acid and the mixture heated to reflux for 5 hours. The toluene was removed in vacuo and the residue triturated with diethyl ether and filtered, 2.6 g. (87% yield).

1. temperatureto reflux for 5 hours
2. customThe toluene was removed in vacuo
3. customthe residue triturated with diethyl ether
4. filtrationfiltered