HCID 20244911, compound → HCID 13644529, compound
Reaction equation
CC1C=C(C2(CC(O)=O)C(=O)NC(=O)N2)C=CC=1.COC1C=C(C2(CC(O)=O)C(=O)NC(=O)N2)C=CC=1.C[C:39]1[CH:48]=[C:47]2[C:42]([CH2:43][C:44](=[O:55])[CH2:45][C:46]32[C:52](=[O:53])[NH:51][C:50](=[O:54])[NH:49]3)=[CH:41][CH:40]=1.COC1C=C2C(CC(=O)CC32C(=O)NC(=O)N3)=CC=1>>[C:46]12([C:52](=[O:53])[NH:51][C:50](=[O:54])[NH:49]1)[C:47]1[C:42](=[CH:41][CH:40]=[CH:39][CH:48]=1)[CH2:43][C:44](=[O:55])[CH2:45]2Participants
5
Procedure
Starting with 4-(m-methylphenyl)-4-(carboxymethyl)imidazolidine 2,5-dione and 4-(m-methoxyphenyl)-4-(carboxymethyl) imidazolidine 2,5-dione and following the procedures of Example 2H-2E, 3',4'-dihydro-7'-methylspiro[imidazolidine-4,1'(2'H)-naphthalene]2,3',5-trione and 3',4'-dihydro-7'-methoxyspiro[imidazolidine-4,1'(2'H)-naphthalene]2,3',5-trione are prepared, respectively.
Workup
- customare prepared
Sources & evidence
- ORD record
- ord-434684593d67468b9401ae6fc2e54a2b
- Source dataset
- uspto-grants-1986_03
- Patent number
- US04575507
Reaction notes
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