Bromine → HCID 20244877, compound

HRID 482697Notes

Reaction equation

HRID 482697 reaction equation
[ClH:1].Cl.[NH2:3][C:4]1[S:21][C:7]2[CH2:8][CH2:9][N:10]([CH2:13][C:14]3[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=3)[CH2:11][CH2:12][C:6]=2[CH:5]=1.[S-:22][C:23]#[N:24].[K+].BrBr>>[ClH:20].[ClH:1].[NH2:24][C:23]1[S:22][C:5]2[C:6]3[CH2:12][CH2:11][N:10]([CH2:13][C:14]4[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][CH:15]=4)[CH2:9][CH2:8][C:7]=3[S:21][C:4]=2[N:3]=1

Participants

4

Reactant 3

HCID 24408BromineHCID 516872Potassium thiocyanateHCID 20244862HCID 20244862, compound

Product 1

HCID 20244877HCID 20244877, compound

Procedure

This compound was prepared from 2-amino-6-(4-chlorobenzyl)-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine dihydrochloride, potassium thiocyanate and bromine analogous to Example 1.

Sources & evidence

ORD record
ord-8a7644c8b946462f83d97246e8dd1986
Source dataset
uspto-grants-1986_03
Patent number
US04575504

Reaction notes

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