Bromine → HCID 20244848, compound

HRID 482701Notes

Reaction equation

HRID 482701 reaction equation
Cl.[NH2:2][C:3]1[S:16][C:6]2[CH2:7][CH2:8][N:9]([C:12](=[O:15])[CH2:13][CH3:14])[CH2:10][CH2:11][C:5]=2[CH:4]=1.[S-:17][C:18]#[N:19].[K+].BrBr>>[NH2:19][C:18]1[S:17][C:4]2[C:5]3[CH2:11][CH2:10][N:9]([C:12](=[O:15])[CH2:13][CH3:14])[CH2:8][CH2:7][C:6]=3[S:16][C:3]=2[N:2]=1

Participants

4

Reactant 3

HCID 24408BromineHCID 516872Potassium thiocyanateHCID 20244872HCID 20244872, compound

Product 1

HCID 20244848HCID 20244848, compound

Procedure

This compound was prepared from 2-amino-6-propionyl-5,6,7,8-tetrahydro-4H-thieno[2,3-d]azepine hydrochloride, potassium thiocyanate and bromine analogous to Example 1.

Sources & evidence

ORD record
ord-f82effd2990d411690c3ecf6aa3ba886
Source dataset
uspto-grants-1986_03
Patent number
US04575504

Reaction notes

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