Isopropanol → HCID 70467063, Verbindung

HRID 482703Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 482703
[NH2:1][C:2](=[N:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[CH:14]=1)=[O:11])[N:3]([CH3:8])[CH2:4][C:5]([OH:7])=[O:6].[CH3:20][CH:21](O)[CH3:22]>Cl>[ClH:19].[NH2:1][C:2](=[N:9][C:10]([NH:12][C:13]1[CH:18]=[CH:17][CH:16]=[C:15]([Cl:19])[CH:14]=1)=[O:11])[N:3]([CH3:8])[CH2:4][C:5]([O:7][CH:21]([CH3:22])[CH3:20])=[O:6]

Komponenten

4

Edukt 2

HCID 3776IsopropanolHCID 54025116N-{amino[(3-chlorophenyl)aminocarbonyl]iminomethyl}-N-methylglycine

Produkt 1

HCID 70467063HCID 70467063, VerbindungAusbeute 55 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 313Hydrochloric AcidLösungsmittel

Versuchsvorschrift

A 5.0 g sample of N-{amino[(3-chlorophenyl)aminocarbonyl]iminomethyl}-N-methylglycine was stirred in 200 ml of 4% hydrogen chloride in 2-propanol for 30 minutes. The undissolved solid was removed by filtration. The filtrate was stirred for 24 hours at 25°. The solution was cooled and the precipitated white crystalline 2-propyl N-{amino[(3-chlorophenyl)aminocarbonyl]iminomethyl}-N-methylglycinate, 3.5 g (55% yield), was collected and dried, m.p. 185° C. (d).

Aufarbeitung

  1. customThe undissolved solid was removed by filtration
  2. temperatureThe solution was cooled
  3. customthe precipitated white crystalline 2-propyl N-{amino[(3-chlorophenyl)aminocarbonyl]iminomethyl}-N-methylglycinate, 3.5 g (55% yield), was collected
  4. customdried

Quellen und Nachweise

ORD-Eintrag
ord-3296701f28fa4d82bf57a33cadd6d2e3
Quelldatensatz
uspto-grants-1986_03
Patentnummer
US04575514

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