Toluene → 4-Formylbenzoyl chloride

Participants

Reaction Steps

The title substance was synthesized as follows: 300 ml of thionyl chloride was dropped into a mixture of 358 g of commercially available terephthalaldehydic acid with 700 ml of toluene and 2 g of pyridine, and the solution was heated under reflux slowly until a homogeneous reaction solution was obtained. After the solution was cooled to room temperature, unreacted thionyl chloride and toluene as a solvent were distilled off in vacuum. Terephthalaldehydic acid chloride (b.p. 133°-135° C./15 Torr) was obtained by the vacuum distillation of the remaining reaction product.

Provenance & Evidence