Tetrahydrofuran → HCID 14030534, compound

Participants

Reaction Steps

A dry 3-l flask equipped with a mechanical stirrer is charged with 145.85 g of mono-p-nitrobenzylmalonate (0.61 moles) and 1365 ml of anhydrous tetrahydrofuran. After 15 minutes 35.4 g of magnesium ethoxide (0.31 moles) are added and the reaction mixture is stirred for two hours. The resulting clear solution is then added over a period of one hour to 2 liters of ethyl ether kept at 0° C. by an ice bath. After a further hour at 0° C. the resulting solid is filtered under vacuum and dried in vacuo to yield 144 g (94%) of magnesium mono-p-nitrobenzylmalonate.

Provenance & Evidence