Benzyl bromoacetate → HCID 20243506, compound

Participants

Reaction Steps

A solution of aminoacetaldehyde dimethyl acetal (2.2 ml, 0.04 mole) in ether (10 ml) was cooled to 0° C. Benzyl bromoacetate (1.6 ml, 0.02 mole) was added. After stirring at ambient temperature overnight, the solid aminoacetaldehyde dimethyl acetal hydrobromide was filtered and the solution was concentrated to an oil. Flash chromatography on silica (LPS-1) (40:60 ethyl acetate:hexane eluant) gave 2.2 gms of the purified title compound.

Provenance & Evidence