3-Octadecyl-2-morpholinocarbonyl-1-tritylglycerol → 3-Octadecyl-2-morpholinocarbonylglycerol

HRID 482948Notes

Reaction equation

[CH2:1]([O:19][CH2:20][CH:21]([O:43][C:44]([N:46]1[CH2:51][CH2:50][O:49][CH2:48][CH2:47]1)=[O:45])[CH2:22][O:23]C(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]>C(O)(=O)C>[CH2:1]([O:19][CH2:20][CH:21]([O:43][C:44]([N:46]1[CH2:51][CH2:50][O:49][CH2:48][CH2:47]1)=[O:45])[CH2:22][OH:23])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

Conditions

Temperature: 100 °C

Procedure

The glycerol compound (2.7 g) obtained in Example 42 was dissolved in 30 ml of 80% acetic acid, and the solution was heated at 100° C. for an hour. The solvent was then distilled off and the residue was purified by silica gel column chromatography to give 1.3 g of the above-identified compound melting at 48°-49° C.

Workup

distillationThe solvent was then distilled off
customthe residue was purified by silica gel column chromatography

Sources & evidence

ORD record: ord-5a9ac620da954d5c98bda20d065a6d12
Source dataset: uspto-grants-1986_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04576933

Reaction notes

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