Benzimidazole → 4-[2-(1H-Benzimidazol-1-yl)ethoxy]phenol

HRID 482989Notes

Reaction equation

HRID 482989 reaction equation
C([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15][CH2:16][CH2:17]Br)=[CH:11][CH:10]=1)C1C=CC=CC=1.[N:19]1[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=2[NH:21][CH:20]=1>>[N:19]1([CH2:17][CH2:16][O:15][C:12]2[CH:11]=[CH:10][C:9]([OH:8])=[CH:14][CH:13]=2)[C:23]2[CH:24]=[CH:25][CH:26]=[CH:27][C:22]=2[N:21]=[CH:20]1

Participants

3

Reactant 2

HCID 5798BenzimidazoleHCID 107570881-(Benzyloxy)-4-(2-bromoethoxy)benzene

Product 1

HCID 202052654-[2-(1H-Benzimidazol-1-yl)ethoxy]phenol

Procedure

In a manner analogous to that described in Example 1(b), from 1-benzyloxy-4-(2-bromoethoxy)benzene and benzimidazole, 4-[2-(1-benzimidazolyl)ethoxy]phenol was obtained.

Sources & evidence

ORD record
ord-4dcfef4bb151462287574e57136fb914
Source dataset
uspto-grants-1986_03
Patent number
US04577030

Reaction notes

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