1H-1,2,4-Triazole → 4-[2-(1H-1,2,4-triazol-1-yl)ethoxy]phenol

HRID 482990Notes

Reaction equation

HRID 482990 reaction equation
[CH2:1]([O:8][C:9]1[CH:14]=[CH:13][C:12]([O:15]CCBr)=[CH:11][CH:10]=1)[C:2]1C=CC=CC=1.[NH:19]1[CH:23]=[N:22][CH:21]=[N:20]1>>[N:19]1([CH2:2][CH2:1][O:8][C:9]2[CH:14]=[CH:13][C:12]([OH:15])=[CH:11][CH:10]=2)[CH:23]=[N:22][CH:21]=[N:20]1

Participants

3

Reactant 2

HCID 92571H-1,2,4-TriazoleHCID 107570881-(Benzyloxy)-4-(2-bromoethoxy)benzene

Product 1

HCID 202052824-[2-(1H-1,2,4-triazol-1-yl)ethoxy]phenol

Procedure

In a manner analogous to that described in Example 1(b), from 1-benzyloxy-4-(2-bromoethoxy)benzene and 1H-1,2,4-triazole, 4-[2-(1H-1,2,4-triazol-1-yl)ethoxy]phenol was obtained.

Sources & evidence

ORD record
ord-75201d8d1e3a46d085321010c812b65a
Source dataset
uspto-grants-1986_03
Patent number
US04577030

Reaction notes

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