Methanol → HCID 178475130, compound

Participants

Reaction Steps

1-Amino-5-mercapto-1H-tetrazole (4.18 g) was dissolved in tetrahydrofuran (30 ml), and acetic anhydride (4.01 g) was added thereto. The mixture was refluxed for 6 hours and then condensed under reduced pressure to remove solvent. Methanol (4 ml) was added to the residue thus obtained, and the methanol solution was allowed to stand at room temperature for 20 minutes. The mixture was evaporated to remove solvent. Hot isopropanol was added to the residue thus obtained, and the solution was allowed to stand at room temperature. Crystalline precipitates were collected by filtration. 4.71 g of 1-acetamido-5-mercapto-1H-tetrazole were obtained as colorless needles. mp 147°-148° C. (decomp.)

Provenance & Evidence