HCID 13262012, compound → HCID 178508493, compound

Participants

Reaction Steps

A solution of 7β-[2-(2-tritylaminothiazol-4-yl)-(Z)-2-cyclopentyloxyiminoacetamido]-3-[(1-amino-1H-tetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylic acid (2.27 g, 2.8 mmol) in 80% formic acid (11 ml) was stirred at room temperature for 50 minutes and then treated in a manner similar to that described in Example 6, (d) to give pale brown powder of 7β-[2-(2-aminothiazol-4-yl)-(Z)-2-cyclopentyloxyiminoacetamido]-3-[(1-amino-1H-tetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylic acid (0.53 g, 33%).

Provenance & Evidence